Campbell Lab & Teaching Site

Reproductive Endocrinology

Reproductive Biology

Human Reproductive Ecology

Kenneth L. Campbell, Ph.D.
Professor Campbell as Associate Dean, 2006Dr. Campbell at leisure while hiking.Graduation, Spring 2007 Assoc. Dean Campbell with Senator Kerry and future governor Patrick, September 2006 Lecturing, on holiday, at graduation, & serving the campus as Associate Dean of Science & Mathematics (2005-2008).


Home


Contents of this Site 


Campbell Lab Focus

The focus on defining the physiological factors giving rise to interpopulation variations in realized fertility in humans and the development of tools for assessments of these factors.  Ratio of testosterone to LH versus FSH in Gainj (a non-Westernized population in New Guinea) men. This work has helped found the Cover of the proceedings of the first conference on Human Reproductive Ecology. discipline of human reproductive ecology which also includes examination of factors that link diet and disease status to such pertinent phenomena as birth seasonality, male endocrine function, and female conceptive loss.  Exploration of the reproductive Perodicticus potto of central Africa. biology of a captive prosimian and the effects of diet on steroid catabolism in other species has expanded applications of our methods beyond humans.  In vitro studies of the measurement and metabolism of several hormones including steroids, gonadotropins and inhibin and molecular genetic probing of disease vectors, immune status, female reproductive status and coital patterning both in human and nonhuman species have expanded the variables available for study.  Development of methods for simultaneously and noninvasively measuring ovarian, insemination and urogenital microbial ecology status in serial female urine sediments has expanded the abilities of demographers, epidemiologists and clinicians conducting fertility enhancements.                           PCR demonstration that coital patterns in humans can be tracked using PCR on female urine sediment DNA. Results from a qPCR experiment. MA10 tumor cells binding iodinated hCG (black dots).
Ultimately our work should help define which physiological and ecological parameters are most appropriate for modulation in programs meant to empower couples to regulate the size and spacing of children as well as those most vulnerable to insult and therefore in need of protection with environmental, animal management, public health, nutrition, or care delivery programs.

Notable Publications:

Campbell, KL, JC Rockett (2006) Biomarkers of ovulation, endometrial receptivity, fertilisation, implantation and early pregnancy progression, Paediatric & Perinatal Epidemiology  20 (s1), 13-25.

Campbell, B, P Leslie, KL Campbell (2006) Age-related changes in testosterone and SHBG among Turkana males, Am J Human Biology 18(1):71-82.

Campbell, BC, PW Leslie, KL Campbell, MA Little (2005) Pubertal timing, hormones and body composition among adolescent Turkana males. Am J Phys Anthrop 128(4):896-905.

Lukas, WD, BC Campbell, KL Campbell (2005) Urinary cortisol and muscle mass in Turkana men, Am J Hum Biology 17(4):489–495.

<>O'Connor, KA, E Brindle, JB Shofer, RC Miller, NA Klein, MR Soules, KL Campbell, C Mar, MS Handcock (2004) Statistical correction for non-parallelism in a urinary enzyme immunoassay, Journal of Immunoassay and Immunochemistry 25(3):259-278.

O'Connor KA, Brindle E, Holman DJ, Klein NA, Soules MR, Campbell KL, Kohen F, Munro CJ, Shofer J, Lasley WL, Wood JW (2003) Urinary estrone conjugate and pregnanediol-3-glucuronide enzyme-immunoassays for population research, Clinical Chemistry 49(7):1139-1148.

Campbell BC, WD Lukas, KL Campbell (2001) Reproductive ecology of male immune function and gonadal function. In PT Ellison (ed) Reproductive Ecology and Human Evolution. Hawthorne, NY: Aldine De Gruyter, 159-178.

Holman DJ, JW Wood, KL Campbell (2000) Age-dependent decline of female fecundity is caused by early fetal loss. Chap. 9 in te Velde ER,Broekmans F, Pearson P, eds. Female Reproductive Ageing, Studies in Profertility Series, 9:123-136 Carnforth, UK: Parthenon Publishing Group.

Schultheiss, OC, KL Campbell & DC McClelland (1999) Implicit power motivation moderates men's testosterone responses to imagined and real dominance success, Hormones and Behavior 36:234-241.

Campbell, KL, OC Schultheiss, & DC McClelland (1999) A necessary adjustment of protocol for use of DPC coated-tube testosterone assay with saliva, Clinical Biochemistry 32(1):83-85.

Leslie, PW, KL Campbell, BC Campbell, CS Kigondu, and LW Kirumbi (1999) Fecundity and fertility.  Chap. 13 in MA Little and PW Leslie, eds.  Turkana Herders of the Dry Savanna: Ecology and Biobehavioral Response of Nomads to an Uncertain Environment. Oxford Univ. Press:Oxford. 249-280.

Holman, D, FN Rasheed, CM Stroud, E Brindle, KA O'Connor & KL Campbell (1998) A commercial pregnancy test modified for field studies of fetal loss, Clinica Chimica Acta, 271(1):25-44.

Leslie, PW, KL Campbell, MA Little, CS Kigondu (1996) Evaluation of reproductive function in Turkana women with enzyme-immunoassays of urinary hormones in the field, Hum Biol 68:95-117.

Campbell, KL & JW Wood, Eds (1994) Human Reproductive Ecology: Interactions of Environment, Fertility and Behavior, Annals NYAS, 709. New York: New York Academy of Sciences.

Campbell, KL (1994) Blood, urine, saliva and dip-sticks: Experiences in Africa, New Guinea, and Boston, In Campbell, KL & JW Wood (ed) Human Reproductive Ecology: Interactions of Environment, Fertility and Behavior, Annals NYAS, 709. New York: New York Academy of Sciences, 313-331.

Campbell, KL & JW Wood (1994) An introduction to quantitative endocrinology. Appendix In JW Wood Dynamics of Human Reproduction: Biology, Biometry, Demography. Hawthorne, NY: Aldine De Gruyter, 553-590.

Leslie, PW, KL Campbell, & MA Little (1993) Pregnancy loss in nomadic and settled women in Turkana, Kenya: A prospective study, Hum Biol, 65:237-254.

Campbell, K & J Wood (1988) Fertility in traditional societies. In P Diggory, M Potts & S Teper (ed) Natural Human Fertility: Social and Biological Determinants. London: Macmillan Press Ltd, 39-69.

Campbell, KL (1988) Solid-state assays: reagents and film technology for dip-stick assays. In B Albertson & F Haseltine (ed) Non-Radiometric Assays: Technology and Application in Polypeptide and Steroid Hormone Detection. New York: Alan R Liss, 237-287.

Wood, JW, PL Johnson & KL Campbell (1985) Demographic and endocrinological aspects of low natural fertility in highland New Guinea, J Biosoc Sci 17:57-79.

Wood, JW, PL Johnson, D Lai, I Maslar & KL Campbell (1985) Lactation and birth-spacing in highland New Guinea, J Biosoc Sci Suppl 9:159-173.

Landefeld, TD, MD Byrne, KL Campbell & AR Midgley (1981) Differential processing of the two subunits of human choriogonadotropin (hCG) by granulosa cells. I. Preparation and characterization of selectively labeled human choriogonadotropin, Endocrinology 109:1851-1857.

Campbell, KL, P Bagavandoss, MD Byrne, JA Jonassen, TD Landefeld, MW Quasney, MM Sanders & AR Midgley (1981) Differential processing of the two subunits of human choriogonadotropin (hCG) by granulosa cells. II. In vivo studies, Endocrinology 109:1858-1871.

Campbell, KL (1979) Ovarian granulosa cells isolated with EGTA and hypertonic sucrose: cellular integrity and function, Biol Reprod 21:773-786.


Copyright Notice, Use Conditions, and User Agreements

The materials contained on this Website, including, but not limited to, the textual material, graphics, artwork, photographs, and visual elements are owned or controlled separately (and exclusively as a collective work) by Kenneth L. Campbell, Department of Biology, University of Massachusetts at Boston, Copyright 1997-2003 Kenneth L. Campbell, unless otherwise noted herein. In addition, copyright in the selection, arrangement, and coordination of materials in this Website is owned exclusively by Kenneth L. Campbell, Department of Biology, University of Massachusetts at Boston, Copyright 1997-2003 Kenneth L. Campbell.

Viewers of this Website may only view or browse the Website or make limited copies of portions of this work as fall within the fair use provisions of the Copyright Act, provided all such uses are for noncommercial personal purposes, and further provided that the user maintains all copyright and any other notices on all copies. Users are not permitted to store, in electronic or any other form, any significant portion of this Website. The contents of this Website may not be further reproduced, distributed, transmitted, modified, adapted, displayed, published, or sold in whole or in part without the prior written permission of Kenneth L. Campbell, Department of Biology, University of Massachusetts at Boston.

Any use which is commercial or non-personal is strictly prohibited, and may subject the User making such uses to applicable civil or criminal penalties.

The User of this Website represents, warrants, and covenants that nothing uploaded, distributed, or published on this Website will be used in a libelous, defamatory, obscene, pornographic, or abusive way nor will be used to invade the rights of privacy or other personal or property rights or to infringe the copyright or trademark or any person or entity. The User shall indemnify, defend and hold Kenneth L. Campbell, and/or the Department of Biology, and/or the University of Massachusetts at Boston, harmless from any damages, expenses, and costs (including reasonable attorneys' fees) arising out of any breach of these Terms and Conditions, representations or warrantees by the user.

As part of this Website the Users may have access to a bulletin board and e-mail to which the User may send messages and other content. Kenneth L. Campbell, Department of Biology, University of Massachusetts at Boston, reserves the right to monitor, delete, edit, remove, modify, or transmit any message or submission by a User of this bulletin board or e-mail. The Users shall remain solely responsible for the content of their messages. The User warrants that any and all moral rights in any uploaded materials have been waived.

Kenneth L. Campbell, and/or the Department of Biology, and/or the University of Massachusetts at Boston, shall not be responsible for communications or activities occurring outside the context of the bulletin board or associated e-mail even if such communication of activity commences or continues in the context of the bulletin board or associated e-mail. The User further represents and warrants to Kenneth L. Campbell, Department of Biology, University of Massachusetts at Boston that the bulletin board and associated e-mail will not be used for the solicitation of funds, advertising, or solicitation of goods or services. The User shall hold Kenneth L. Campbell, and/or the Department of Biology, and/or the University of Massachusetts at Boston, harmless from any damages, expenses, and costs (including reasonable attorneys' fees) arising out of any breach or alleged breach of the User's implied or expressed representations and warranties.


Issues concerning this Website should be brought

to the attention of Kenneth L. Campbell at

kenneth.campbell@umb.edu

 
© 2009 Kenneth L. Campbell