Kenneth L. Campbell, Ph.D.
Lecturing, on holiday, at graduation, & serving the campus as Associate Dean of Science & Mathematics (2005-2008).
Campbell Lab Focus
We focus on the physiological factors causing inter-population variations in realized fertility in humans and the development of biomarkers and tools for assessing these factors. Our work has helped found the discipline of human reproductive ecology which includes examination of factors that link diet and disease status to such phenomena as birth seasonality, female conceptive loss, male endocrine function, and the urogenital microbiome.
Exploration of the reproductive biology of a captive prosimian has expanded applications of our methods beyond humans. In vitro studies of the measurement and metabolism of several hormones including steroids, gonadotropins and inhibin, hormone binding globulins, and molecular genetic probing of disease vectors, immune status, female reproductive status and coital patterning both in human and nonhuman species have expanded the list of possible study variables. Development of methods for simultaneously and noninvasively measuring ovarian, insemination and urogenital microbiome status in serial female urine sediments has expanded the abilities of demographers, epidemiologists and clinicians conducting fertility enhancements. More recent proteomic exploration of protein hormone metabolism in the context of a search for biomarkers relevant to endocrinology hints at the existence of exciting new avenues for exploration of endocrine regulation and control.
Ultimately our work should help define the physiological and ecological parameters most appropriate for modulation in programs to empower couples to regulate the size and spacing of children and the maintenance of health and full physiological function. In addition it should help to define those most vulnerable to ecological insults and therefore in need of protection with environmental, animal management, public health, nutrition, or care delivery programs.
Campbell, KL, J Kim, N Bruss (2016) Crossing the disciplinary boundary: Pedagogical conjunctions in the humanities and sciences, International Journal of Science in Society 7(4), 27pp; in press.
Campbell, KL, M Lopresti, W Lukas (2014) Inhibition of horseradish peroxidase (HRP) by a nonhydrophobic component of urine: A caution for immunoassays, Open Clin Chem J, 7(1), 1-7.
Campbell, BC, P Leslie, KL Campbell (2007) Age-related pattern of DHEAS among Turkana males of northern Kenya, The Aging Male 10(4):203-209.
Campbell, B, P Leslie, K Campbell (2006) Age-related patterns of urinary gonadotropins (FSH and LH) and E-3-G as measures of reproductive function among Turkana males of Northern Kenya, Social Biology, 53(1-2):30-45.
Campbell, KL, JC Rockett (2006) Biomarkers of ovulation, endometrial receptivity, fertilisation, implantation and early pregnancy progression, Paediatric & Perinatal Epidemiology 20 (s1), 13-25.
Campbell, B, P Leslie, KL Campbell (2006) Age-related changes in testosterone and SHBG among Turkana males, Am J Human Biology 18(1):71-82.
Campbell, BC, PW Leslie, KL Campbell, MA Little (2005) Pubertal timing, hormones and body composition among adolescent Turkana males. Am J Phys Anthrop 128(4):896-905.
Lukas, WD, BC Campbell, KL Campbell (2005) Urinary cortisol and muscle mass in Turkana men, Am J Hum Biology 17(4):489–495.
O'Connor, KA, E Brindle, JB Shofer, RC Miller, NA Klein, MR Soules, KL Campbell, C Mar, MS Handcock (2004) Statistical correction for non-parallelism in a urinary enzyme immunoassay, Journal of Immunoassay and Immunochemistry 25(3):259-278.
O'Connor KA, Brindle E, Holman DJ, Klein NA, Soules MR, Campbell KL, Kohen F, Munro CJ, Shofer J, Lasley WL, Wood JW (2003) Urinary estrone conjugate and pregnanediol-3-glucuronide enzyme-immunoassays for population research, Clinical Chemistry 49(7):1139-1148.
Campbell BC, WD
Lukas, KL Campbell (2001) Reproductive ecology of male immune function and
gonadal function. In PT Ellison (ed)
Reproductive Ecology and Human Evolution. Hawthorne, NY: Aldine De Gruyter, 159-178.
Holman DJ, JW Wood, KL Campbell (2000) Age-dependent decline of female fecundity is caused by early fetal loss. Chap. 9 in te Velde ER,Broekmans F, Pearson P, eds. Female Reproductive Ageing, Studies in Profertility Series, 9:123-136 Carnforth, UK: Parthenon Publishing Group.
Schultheiss, OC, KL Campbell & DC McClelland (1999) Implicit power motivation moderates men's testosterone responses to imagined and real dominance success, Hormones and Behavior 36:234-241.
Campbell, KL, OC Schultheiss, & DC McClelland (1999) A necessary adjustment of protocol for use of DPC coated-tube testosterone assay with saliva, Clinical Biochemistry 32(1):83-85.
Leslie, PW, KL Campbell, BC Campbell, CS Kigondu, and LW Kirumbi (1999) Fecundity and fertility. Chap. 13 in MA Little and PW Leslie, eds. Turkana Herders of the Dry Savanna: Ecology and Biobehavioral Response of Nomads to an Uncertain Environment. Oxford Univ. Press:Oxford. 249-280.
Holman, D, FN Rasheed, CM Stroud, E Brindle, KA O'Connor & KL Campbell (1998) A commercial pregnancy test modified for field studies of fetal loss, Clinica Chimica Acta, 271(1):25-44.
Leslie, PW, KL Campbell, MA Little, CS Kigondu (1996) Evaluation of reproductive function in Turkana women with enzyme-immunoassays of urinary hormones in the field, Hum Biol 68:95-117.
Campbell, KL & JW Wood, Eds (1994) Human Reproductive Ecology: Interactions of Environment, Fertility and Behavior, Annals NYAS, 709. New York: New York Academy of Sciences.
Campbell, KL (1994) Blood, urine, saliva and dip-sticks: Experiences in Africa, New Guinea, and Boston, In Campbell, KL & JW Wood (ed) Human Reproductive Ecology: Interactions of Environment, Fertility and Behavior, Annals NYAS, 709. New York: New York Academy of Sciences, 313-331.
Campbell, KL & JW Wood (1994) An introduction to quantitative endocrinology. Appendix In JW Wood Dynamics of Human Reproduction: Biology, Biometry, Demography. Hawthorne, NY: Aldine De Gruyter, 553-590.
Leslie, PW, KL Campbell, & MA Little (1993) Pregnancy loss in nomadic and settled women in Turkana, Kenya: A prospective study, Hum Biol, 65:237-254.
Campbell, K & J Wood (1988) Fertility in traditional societies. In P Diggory, M Potts & S Teper (ed) Natural Human Fertility: Social and Biological Determinants. London: Macmillan Press Ltd, 39-69.
Campbell, KL (1988) Solid-state assays: reagents and film technology for dip-stick assays. In B Albertson & F Haseltine (ed) Non-Radiometric Assays: Technology and Application in Polypeptide and Steroid Hormone Detection. New York: Alan R Liss, 237-287.
Wood, JW, PL Johnson & KL Campbell (1985) Demographic and endocrinological aspects of low natural fertility in highland New Guinea, J Biosoc Sci 17:57-79.
Wood, JW, PL Johnson, D Lai, I Maslar & KL Campbell (1985) Lactation and birth-spacing in highland New Guinea, J Biosoc Sci Suppl 9:159-173.
Landefeld, TD, MD Byrne, KL Campbell & AR Midgley (1981) Differential processing of the two subunits of human choriogonadotropin (hCG) by granulosa cells. I. Preparation and characterization of selectively labeled human choriogonadotropin, Endocrinology 109:1851-1857.
Campbell, KL, P Bagavandoss, MD Byrne, JA Jonassen, TD Landefeld, MW Quasney, MM Sanders & AR Midgley (1981) Differential processing of the two subunits of human choriogonadotropin (hCG) by granulosa cells. II. In vivo studies, Endocrinology 109:1858-1871.
Campbell, KL (1979) Ovarian granulosa cells isolated with EGTA and hypertonic sucrose: cellular integrity and function, Biol Reprod 21:773-786.
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