PROFESSOR:  Dr. R.A. Nicholson	Office:  B 8278
	Phone:  291-4107

PREREQUISITES:  BISC 313 or permission of the Department
 

DESCRIPTION:  This lecture and laboratory course will focus primarily on the toxicological assessment of environmental chemicals in mammals. It will explore the main principles and quantitative methods upon which this type of evaluation is founded with emphasis on acute, sub-chronic and chronic toxicity, genotoxicity, reproductive and developmental toxicity, neurotoxicity, hepatotoxicity, dermal and ocular toxicity and immunotoxicity.
 

RECOMMENDED TEXT:
A.W. Hayes: Principles and Methods of Toxicology, Raven Press, Third Edition, ISBN 0-7817 0131-7. This text (one copy) and two copies of the second edition will be available on reserve in the SFU Library.
 

GRADING:  The assessment will be based on marks obtained in laboratory write ups (65% of final grade) and a final 2 hour exam (35% of final grade). The exam questions will be based on materials presented in the lectures and topics covered in the laboratory.