Analytical
Assay Performance Parameters
Specificity:
uniqueness of the detected species, lack of
cross-reactivities, parallelism of diluted samples
-
Precision:
reproducibility
of measurements
-
Accuracy:
ability
to estimate the "correct," known, amount of analyte contained in standards
or reference samples; lack of Bias:
comparability
of results with other assays for the same analyte
-
Sensitivity:
(analytically)
slope of the assay response curve, height of the response/amount of analyte
yielding the response; also, (diagnostically) limit of detection or the
lowest measurable, nonzero, amount of analyte