Hormone |
Acronym |
Hypophysial
Cell Type |
Hypothalamic
Regulator(s) |
Hormonal
Function(s) |
Corticotropin, Adrenocorticotropin |
ACTH |
Corticotrope |
+Corticotropin Releasing Hormone, Corticoliberin
(CRH); + Interleukin 1 ; - Glucocortical Steroids (via CRH); + Vasopressin;
+ PACAP |
Stimulates glucocorticoid production by adrenal
fasiculata & reticularis |
Thyrotropin, Thyroid Stimulating Hormone |
TSH |
Thyrotrope |
-Thyroxine (T4); +Thyroid Releasing
Hormone, Thyroliberin (TRH); -Somatostatin (SS) |
Stimulates thyroxine production by thyroid |
Prolactin, Mammotropin, Luteotropin |
PRL |
Lactotrope; Mammotrope |
-Dopamine; + TRH; - SS; + Estrogens; + Oxytocin |
Stimulates milk synthesis by secretory epithelium
of breast; supports corpus luteum function |
Somatotropin, Growth Hormone |
GH |
Somatotrope |
+ Growth Hormone Releasing Hormone, Somatoliberin
(GHRH); - SS; + PACAP |
Stimulates somatic growth, supports intermediary
metabolism |
Follitropin, Follicle Stimulating Hormone |
FSH |
Gonadotrope |
+ Gonadotropin Releasing Hormone, Luteinizing
Hormone Releasing Hormone, Gonadoliberin (GnRH, LHRH); - Inhibin; - Sex
steroids (via LHRH) |
Supports growth of ovarian follicles & estradiol
production; Supports Sertoli cell function & spermatogenesis |
Lutropin, Luteinizing Hormone |
LH |
Gonadotrope |
+ GnRH (LHRH); - Sex steroids (via LHRH in &
); + Estradiol in near midcycle |
Supports late follicular development, ovulation,
& corpus luteum function (especially progesterone synthesis); Supports
testosterone synthesis, Leydig cell |
Melanotropin, Melanocyte Stimulating Hormone |
MSH |
Melanotrope |
+ CRH |
Supports dispersal & synthesis of pigment
in melanocytes; may alter adrenal response to ACTH |